Total Publications - A complete listing of 210 publications organized into categories
DHS (trans-4,4'-dihydroxystilbene) suppresses DNA replication and tumor growth by inhibiting RRM2 (ribonucleotide reductase regulatory subunit M2). Chen CW, Li Y, Hu S, Zhou W, Meng Y, Li Z, Zhang Y, Sun J, Bo Z, DePamphilis ML, Yen Y, Han Z, Zhu W. Oncogene (2018) doi: 10.1038/s41388-018-0584-6. [Epub ahead of print]
CDK1 Inhibition Facilitates Formation of Syncytiotrophoblasts and Expression of Human Chorionic Gonadotropin. Ullah R, Dar S, Ahmad T, de Renty C, Usman M, DePamphilis ML, Faisal A, Shahzad-Ul-Hussan S, Ullah Z. Placenta 66:57-64 (2018).
Links Between DNA Replication, Stem Cells, and Cancer. Vassilev A and DePamphilis ML. Genes (Basel) 8(2) pii: E45 (2017).
Geminin is Essential for Pluripotent Cell Viability During Teratoma Formation, But Not for Differentiated Cell Viability During Teratoma Expansion. Adler-Wailes DC, Kramer JA, DePamphilis ML Stem Cells Dev. 26(4):285-302 (2017).
Identification of genes that are essential to restrict genome duplication to once per cell division. Vassilev A, Lee CY, Vassilev B, Zhu W, Ormanoglu P, Martin SE, DePamphilis ML. Oncotarget 7(23):34956-76 (2016).
Preface to MAMMALIAN PREIMPLANTATION DEVELOPMENT. DePamphilis ML. Curr Top Dev Biol. 120:xiii-xxi (2016).
Genome duplication at the beginning of mammalian development. DePamphilis ML. Curr Top Dev Biol. 120:55-102 (2016).
Geminin is essential to prevent DNA re-replication dependent apoptosis in pluripotent cells, but not in differentiated cells. Huang YY, Kaneko KJ, Pan H, DePamphilis ML. Stem Cells 33(11):3239-53 (2015).
And-1 coordinates with Claspin for efficient Chk1 activation in response to replication stress. Hao J, de Renty C, Li Y, Xiao H, Kemp MG, Han Z, DePamphilis ML, Zhu W. EMBO J. 34(15):2096-110 (2015).
The dual roles of geminin during trophoblast proliferation and differentiation. de Renty C, Kaneko KJ, DePamphilis ML. Dev Biol. 387(1):49-63 (2014).
Cytoplasmic localization of p21 protects trophoblast giant cells from DNA damage induced apoptosis. de Renty C, DePamphilis ML, Ullah Z. PLoS One 9(5):e97434 (2014).
TEAD4 establishes the energy homeostasis essential for blastocoel formation. Kaneko KJ, DePamphilis ML. Development 140(17):3680-90 (2013).
Endoreplication. Zielke N, Edgar BA, DePamphilis ML. Cold Spring Harb Perspect Biol. 5(1):a012948 (2013).
The involvement of acidic nucleoplasmic DNA-binding protein (And-1) in the regulation of prereplicative complex (pre-RC) assembly in human cells. Li Y, Xiao H, de Renty C, Jaramillo-Lambert A, Han Z, DePamphilis ML, Brown KJ, Zhu W. J Biol Chem. 287(51):42469-79 (2012).
"The Octet": Eight Protein Kinases that Control Mammalian DNA Replication. DePamphilis ML, de Renty CM, Ullah Z, Lee CY. Front Physiol. 3:368 (2012).
Checkpoint kinase-1: one actor playing two roles in "maintaining genome integrity". Ullah Z, DePamphilis ML. Cell Cycle 11(10):1873 (2012).
High-throughput screening for genes that prevent excess DNA replication in human cells and for molecules that inhibit them. Lee CY, Johnson RL, Wichterman-Kouznetsova J, Guha R, Ferrer M, Tuzmen P, Martin SE, Zhu W, DePamphilis ML. Methods 57(2):234-48 (2012).