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Eunice Kennedy Shriver National Institute of Child Health and Human Development - Program in Reproductive and Adult Endocrinology
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Section on Implantation and Oocyte Physiology (SIOP)

Head: Alan H. DeCherney, M.D.

Dr DeCherney is smiling.  He is sharply dressed wearing a black suit and purple bowtie
Through basic and translational research, the Section on Implantation and Oocyte Physiology (SIOP) seeks (1) to identify critical cellular and molecular events required for successful implantation in pregnancy and (2) to understand the relationships between such events and pathologies of early pregnancy. Therefore, our objective is to understand the biology of the developing blastocyst, which requires the differentiation of its outer epithelium, the trophectoderm, into invasive trophoblast cells and the maintenance of a cohort of pluripotent embryonic stem cells.

10 Most Recent Publications

Single vitrified blastocyst transfer maximizes liveborn children per embryo while minimizing preterm birth.
Devine K, Connell MT, Richter KS, Ramirez CI, Levens ED, DeCherney AH, Stillman RJ, Widra EA.
Fertil Steril. 2015 Mar 23. pii: S0015-0282(15)00162-4. doi: 10.1016/j.fertnstert.2015.02.032. [Epub ahead of print]
PMID: 25813283

DNA methylome and transcriptome sequencing in human ovarian granulosa cells links age-related changes in gene expression to gene body methylation and 3'-end GC density.
Yu B, Russanova VR, Gravina S, Hartley S, Mullikin JC, Ignezweski A, Graham J, Segars JH, DeCherney AH, Howard BH.
Oncotarget. 2015 Feb 28;6(6):3627-43.
PMID: 25682867

Timing luteal support in assisted reproductive technology: a systematic review.
Connell MT, Szatkowski JM, Terry N, DeCherney AH, Propst AM, Hill MJ.
Fertil Steril. 2015 Apr;103(4):939-946.e3. doi: 10.1016/j.fertnstert.2014.12.125. Epub 2015 Jan 29.
PMID: 25638420

Building a family through in vitro fertilization--economic realities.
Devine K, Stillman RJ, DeCherney AH.
Fertil Steril. 2015 Feb;103(2):357-8. doi: 10.1016/j.fertnstert.2014.12.092. Epub 2014 Dec 17. No abstract available.
PMID: 25527233

Keeping clinicians in research: the Clinical Research/Reproductive Scientist Training Program (CREST) strategy, 2006-2012.
Usadi RS, Alvero R, Armstrong AY, Rebar RW, DeCherney AH, Maddox YT.
Fertil Steril. 2014 Dec;102(6):1542-4. doi: 10.1016/j.fertnstert.2014.09.002. Epub 2014 Oct 18. No abstract available.
PMID: 25439798

Single-donor and double-donor sperm intrauterine insemination cycles: does double intrauterine insemination increase clinical pregnancy rates?
Zarek SM, Hill MJ, Richter KS, Wu M, DeCherney AH, Osheroff JE, Levens ED.
Fertil Steril. 2014 Sep;102(3):739-43. doi: 10.1016/j.fertnstert.2014.05.018. Epub 2014 Jun 14.
PMID: 24934490

The Affordable Care Act: early implications for fertility medicine.
Devine K, Stillman RJ, DeCherney AH.
Fertil Steril. 2014 May;101(5):1224-7. doi: 10.1016/j.fertnstert.2014.01.024. Epub 2014 Feb 27. Review. No abstract available.
PMID: 24582184

Physician responsibility when a surrogate mother breaks her contract.
Rafique S, DeCherney AH.
Virtual Mentor. 2014 Jan 1;16(1):10-6. doi: 10.1001/virtualmentor.2014.16.01.ecas2-1401. No abstract available.
PMID: 24433656

Ovarian reserve and subsequent assisted reproduction outcomes after methotrexate therapy for ectopic pregnancy or pregnancy of unknown location.
Hill MJ, Cooper JC, Levy G, Alford C, Richter KS, DeCherney AH, Katz CL, Levens ED, Wolff EF.
Fertil Steril. 2014 Feb;101(2):413-9. doi: 10.1016/j.fertnstert.2013.10.027. Epub 2013 Nov 20.
PMID: 24269042

Progesterone luteal support after ovulation induction and intrauterine insemination: a systematic review and meta-analysis.
Hill MJ, Whitcomb BW, Lewis TD, Wu M, Terry N, DeCherney AH, Levens ED, Propst AM.
Fertil Steril. 2013 Nov;100(5):1373-80. doi: 10.1016/j.fertnstert.2013.06.034. Epub 2013 Jul 19. Review.
PMID: 23876537

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