- Collective migration of the Posterior Lateral Line primordium.
- Formation of neuromasts within the migrating primordium.
- Specification of a central sensory hair cell progenitor within in protoneuromast.
- The pattern of neuromast deposition by the migrating primordium.
Our expectation is that understanding the genetic regulatory network that coordinates cell fate and morphogenesis of the zebrafish lateral line system will ultimately have a profound impact on translational studies that address a wide range of issues including the development and regeneration of sensory systems and therapies directed at limiting the spread of cancer through metastasis.