...
Our NIH research protocol focuses on the genetics, diagnosis, localization, and surgical and interventional radiological treatment of pheochromocytoma and paraganglioma.
| Div | ||
|---|---|---|
| ||
|
...
Specifically, the development of an animal model of metastatic pheochromocytoma or paraganglioma is crucial in testing various treatment modalities. Recently, we We have introduced this metastatic model and used it successfully in experimental treatment approaches, including LB-1 compound. The studies of genomics and proteomics play an important role in the pathogenesis of metastatic disease and thus allow for earlier detection of malignancy or metastatic disease, which is an important part of our basic science studies. Those techniques helped us to identify some markers that can be very useful to predict metastasis or detect SDHx-related pheochromocytoma or paraganglioma.
...
Dr. Karel Pacak, an internationally recognized leader in the study of pheochromocytoma/paraganglioma, is the principal investigator for this research team. Dr. Pacak has published over 300 articles on pheochromocytoma/paraganglioma and has authored several books and book chapters, with more than 14 than 20 years of experience with patients suffering from this disease.
...
